Cas nhamba: 171599-83-0 Molecular Formula: C 2 2 H 3 0 N 6 O 4 S·C 6 H 8 O 7 = 666.70
| Melting Point | 49-53° |
| Density | 1.05 g/cm³ |
| kuchengetedza temp | nzvimbo inotonhorera, yakaoma uye kudzivirira kuratidzwa kune chiedza kana kupisa kwakanyanya |
| solubility | inonyungudika nyore mu ethanol, acetone, ether, benzene uye methylene chloride, asi isinganyungudika mumvura. |
| optical chiitiko | [α]D20 = +61.0° (ethanol solution) |
| Chitarisiko | chena kusvika kuchiedza yero yecrystalline upfu |
Panguva yekukurudzira pabonde, iyo parasympathetic nerve, non adrenergic uye non cholinergic nerve (NANC) magumo uye vascular endothelial masero anoburitsa nitric oxide (NO) pasi pekuita kwenitric oxide synthase (NOS).Mutsinga dzeropa, soluble guanylate cyclase (sGC) inowanzoitwa neNO, uye sGC inoshanda pa guanosine triphosphate kugadzira cGMP.Iyo cGMP mu corpus cavernosum yepeni inoshandisa yakasimba vasodilator mhedzisiro nekudzikisa kusungirirwa kweCa2 + mumasero anotsvedzerera emhasuru ye corpus cavernosum, zvichikonzera kuzorora kwemaseru akatsetseka uye kuwedzera kwekuyerera kweropa mukati me corpus cavernosum, inotungamira. kune erection.Jinyang alkali inoderedza dhigirii yekuora kwecGMP, nekudaro kuchengetedza kuzorora kweCGMP pane corpus cavernosum yepeni uye kukonzera penile erection.Mu vivo, cGMP yakaderedzwa uye haina kuitwa nePDE5.
Inokodzera kurapa erectile dysfunction (ED) yepeni, inoshanda kune erectile dysfunction inokonzerwa nekushandisa antidepressants, antipsychotics, uye antihypertensive zvinodhaka, pamwe nekutadza kwe erectile kunokonzerwa nekuvhiyiwa kana kushungurudzika.
Inogona kugadzirwa kuita mahwendefa, mapiritsi, yakaoma capsules, akapfava capsules, uye inogona kushandiswa semishonga waini, remuromo mvura, kofi, granules, chewable mapiritsi, lozenges, chewing gum, uye mamwe dosage mafomu.Kune vanhu vakuru, muyero unofanirwa kuva 10-100mg pazuva, iyo inogona kuwedzerwa kana kuderedzwa zvichienderana nemamiriro emushandisi.Zviri nani kuitora padumbu risina chinhu (kunyanya kudzivisa kuitora nemafuta akawanda ezvokudya), uye usanwa doro usati washandisa Tea (kutora hakufaniri kudyiwa panguva imwe chete, izvo hazvirevi kuti kunwa doro panguva imwe chete. nguva inogona kuderedza zvakanyanya erectile basa reViagra).
Nguva inoshanda: Vanhu vazhinji vanoitora kweawa imwe kuti iite.Inokurudzirwa kutora mishonga inenge 1 awa isati yaita zvepabonde, nemigumisiro yaro inogara kwemaawa 48 kusvika kumaawa 72, uye mamwe anogona kugara kwemaawa 116.
