Rifampicin Cas nhamba: 13292-46-1 Molecular Formula: C43H58N4O12

Tsanangudzo Pfupi:

Molecular Formula:
C43H58N4O12

Anoreva zvakafanana:9,17,19,21-hexahydroxy-23-methoxy-2,4,12,1///;2,7-(epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b) furan-1,11(2-h) -dione,5,6;3-(((4-methyl-1-piperazinyl)imino)methyl)-rifamyci;3-((4-methyl-1-piperazinyl)iminomethyl) )rifamycinsv;8-(((4-methyl-1-piperazinyl)imino)methyl)rifamycinsv;8-(4-Methylpiperazinyliminomethyl)rifamycinSV;8-(n-(4-methyl-1-piperazinyl)formidoyl)-rifomycins; RIFAMPIN "LEPETIT"

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Product Detail

Product Tags

Products Specification

Melting Point	183 °
Density	1.1782 (yakaomarara fungidziro)
kuchengetedza temp	2-8°C
solubility	chloroform: soluble50mg/mL, yakajeka
optical chiitiko	N/A
Chitarisiko	kupera simba kutsvuku kusvika kune kusviba kutsvuku
Kuchena	≥99%

Tsanangudzo

Rifampicin is semisynthetic derivative ye rifamicin B, macrolactam antibiotic uye imwe yemishonga inorwisa mabhakitiriya inopfuura mashanu kubva musanganiswa we rifamicins A, B, C, D, uye E, unonzi rifamicin complex, unogadzirwa ne actinomycetes Streptomyces mediteranei ( Nocardia mediteranei).Yakatangwa mukuita zvekurapa muna 1968. Synthesis ye rifampicin inotanga nemushonga we aqueous we rifamicin, iyo pasi pemamiriro ekuita inoiswa oxidized kune itsva inobva ku rifamicin S (32.7.4), nekuumbwa kwepakati kwerifamicin O (32.7. 3).Kudzikisa chimiro chequinone chechigadzirwa ichi nehydrogen uchishandisa palladium pacarbon catalyst inopa rifamicin SV (32.7.5).Chigadzirwa chinoguma chinopinda aminomethylation nemusanganiswa we formaldehyde uye pyrrolidine, kupa 3-pyrrolidinomethylrifamicin SV (32.7.6).Oxidizing chigadzirwa chine lead tetracetate kune enamine uye yakatevera hydrolysis ine aqueous solution ye ascorbic acid inopa 3-formylrifamicin SV (32.7.7).Kuita izvi ne1-amino-4-methylpiperazine kunopa rifampicin inodiwa (32.7.8).

kushandiswa uye dosage

Rifampin inoshandiswa semushonga unorwisa mabhakitiriya.Inobva semisynthetic ye rifamycin B, mushonga unorwisa macrocyclic unogadzirwa ne mold Streptomyces mediterranei.Rifampin inoshandiswa pakurapa tibhii, brucellosis, Staphlococcus aureus, uye zvimwe zvirwere zvinotapukira.