Orlistat Cas nhamba: 132539-06-1 Molecular Formula: C28H29NO
| Melting Point | 195-200°C |
| Density | 1.4 g/cm³ |
| kuchengetedza temp | 2-8℃ |
| solubility | isinganyungudika mumvura, inonyungudika zvishoma mu ethanol, inonyungudika nyore mu chloroform uye methanol |
| optical chiitiko | +71.6 (c=1.0, ethanol) |
| Chitarisiko | chena kana kure-white crystalline powder |
Olistat inogara kwenguva refu, yakananga gastrointestinal lipase inhibitor iyo inogona kudzivirira iyo hydrolysis ye triglycerides mune inonwiwa yemahara fatty acids uye monoacylglycerols, ichivadzivirira kubva pakunyura, nekudaro ichidzikisa calorie kudya uye kudzora uremu.Kana yakashandiswa semushonga wepamusoro-the-counter wekuzvirapa, orlistat inokodzera kurapwa kwevarwere vakafuta kana vakafutisa (ine body mass index ye ≥ 24 uye inofungidzirwa kuverenga kwehuremu / urefu 2).
Orlistat inodhaka yekurasikirwa nehuremu, inotengeswa seXenical.
Olistat inotorwa kubva kulipstatin.Lipstatin inoshanda yakasikwa pancrelipase inhibitor yakaparadzaniswa kubva kuStreptomyces toxitricini Inonyanya kushanda pamaturakiti emudumbu.Inogona kuvharidzira ma enzymes anodiwa nemararamiro emagetsi kuti agaye mafuta, kusanganisira pancreatic ester uye gastric ester, uye kuderedza kubatwa kwegastrointestinal ester kumafuta kuti ibatsire kuderedza uremu, asi ichiri kuda kusanganiswa nekurovedza muviri uye kudya kuti uremerwe uremu.
Iyo yakakurudzirwa dosage yeOlistat capsules ndeye 0.12g capsules inotorwa nekudya kana mukati meawa imwe mushure mekudya.Kana pane chikafu chisina kudyiwa kana chikafu chisina mafuta, mushonga mumwe unogona kusiiwa.Mhedzisiro yekurapa kwekushandiswa kwenguva refu kweorlistat capsules, kusanganisira kudzora uremu uye kuvandudzwa kwezvinhu zvine njodzi, inogona kutsigirwa.Kudya kwemurwere kunofanirwa kuve nekudya kwakaringana, nekudya kwakaderera kwekoriori.Inenge 30% yekoriori yekudya inobva kumafuta, uye chikafu chinofanira kunge chakapfuma muzvibereko nemiriwo.
