Phenformin Cas nhamba: 834-28-6 Molecular Formula: C10H16N8
| Melting Point | 150-155 ℃ |
| Density | 1.197g/cm³ |
| kuchengetedza temp | 2-8℃ |
| solubility | Iine kumwe kunyungudika mumvura, inonyungudika zviri nyore mumethanol uye isopropanol, uye inonetsa kunyungudika muchloroform uye ether. |
| optical chiitiko | +27.0 madhigirii (C=1, mvura). |
| Chitarisiko | white crystalline powder |
Phenformin inonyanya kushandiswa kurapa chirwere cheshuga chisiri insulin chinotsamira kune vanhu vakuru uye chirwere cheshuga chinoenderana ne insulin.Basa racho nderekusimudzira kutora uye glycolysis yeglucose nemasero emhasuru, kuderedza kugadzirwa kweglucose nechiropa, uye kuva neanti hyperglycemic effect.Inogona kushandiswa pamwe chete ne insulin, zvichiita kuti zvive nyore kudzora shuga yeropa uye kuderedza insulin dosage.Kune chirwere cheshuga chakakora, chinogona zvakare kushandiswa kurambidza kudya uye kutora glucose muura kuderedza uremu.
Phenformin inonyanya kushandiswa kurapa chirwere cheshuga chisiri insulin chinotsamira kune vanhu vakuru uye chirwere cheshuga chinoenderana ne insulin.Basa racho nderekusimudzira kutora uye glycolysis yeglucose nemasero emhasuru, kuderedza kugadzirwa kweglucose nechiropa, uye kuva neanti hyperglycemic effect.Inogona kushandiswa pamwe chete ne insulin, zvichiita kuti zvive nyore kudzora shuga yeropa uye kuderedza insulin dosage.Kune chirwere cheshuga chakakora, chinogona zvakare kushandiswa kurambidza kudya uye kutora glucose muura kuderedza uremu.
Oral administration: Iyo inowanzoshandiswa dosage ndeye 50-200mg pazuva, inotorwa mumatatu matatu.Pakutanga, tora 25mg kamwe, 2-3 kanomwe pazuva, usati wadya.Inogona kuwedzera zvishoma nezvishoma kusvika ku50-100mg pazuva.Kazhinji, shuga yeropa inoderera mushure mevhiki imwe yemishonga, asi kuti usvike pahuwandu hwehuga hweropa, mushonga unoda kupfuurira kwemavhiki 3-4.
