Nhamba yeCas: 21187-98-4 Molecular Formula
Melting Point | 163-169 °C |
Density | 1.2205 (yakaomarara fungidziro) |
kuchengetedza temp | Mamiriro ekunze akadzikama, Tembiricha yemumba 2-8°C |
solubility | methylene chloride: soluble |
optical chiitiko | N/A |
Chitarisiko | Off-White Solid |
Kuchena | ≥98% |
is oral antihyperglycemic agent inoshandiswa kurapa chirwere cheshuga mellitus type II.Iyo ndeye sulfonylurea kirasi ye insulin secretagogues, iyo inomutsa β masero epancreas kuburitsa insulin.inosungira kune β cell sulfonyl urea receptor (SUR1), ichienderera mberi ichivharira ATP inonzwisisika potassium nzira.Naizvozvo, iyo potassium efflux inodzikira zvakanyanya, zvichikonzera depolarization yemasero β.Ipapo magetsi-anotsamira calcium machani mu β cell anovhurika, zvichikonzera kudzikamisa activation, izvo zvinozotungamira kune exocytosis ye insulin ine secretorty granules.Zvidzidzo zvenguva pfupi yapfuura zvakaratidzawo kuti zvinogona kuvandudza maitiro e-anti-oxidant uye nitric oxide-mediated vasodilation muType 2 chirwere cheshuga uye kudzivirira pancreatic beta-masero kubva mukukuvadzwa nehydrogen peroxide.
is oral hypoglycemic agent inoshandiswa kurapa chirwere cheshuga chisingaiti insulini.Kurapa kwechirwere cheshuga chinosangana nekufutisa kana chirwere chevascular, kune vanhu vakuru vane chirwere cheshuga 2. Chirwere cheshuga chirwere chisingaperi (chinogara kwenguva refu) chinokanganisa kuti muviri wako unoshanduka sei. zvokudya kuva simba.inoderedza mazinga eshuga yeropa nekukurudzira insulin secretion kubva kuma-β-masero ezvitsuwa zveLangerhans.