Florfenicol Cas nhamba: 73231-34-2 Molecular Formula: C12H14Cl2FNO4S
2,2-dichloro-n-[(1r,2s)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
AQUAFEN FLORFENICOL NUFLOR
[r-(r*, r*)]-n-[1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulforyl)phenyl)-ethyl]-2,2-dichloroacetamide
[R-(R*,S*)]-2,2-DICHLORO-N-[1-(FLUOROMETHYL)-2-HYDROXY-2-[4-(METHYLSULFONYL)PHENYL]ETHYL]ACETAMIDE
SCH-25298
(r-(r*,s*))-methyleste
2,2-dichloro-n-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl
4-(2-((dichloroacetyl)amino)-3-fluoro-1-hydroxypropyl)-benzenesulfonicaci
Florfeniol
FLUPROFEN
Fluorothiamphenicol
Sch-25298, Aquafen
Acetamide, 2,2-dichloro-N-(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-4-(methylsulfonyl)phenylethyl-
2,2-Dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2--[4-(methylsulfonyl)phenyl]ethyl]acetamide
Aquaflor
Aquafen, Nuflor, SCH-25298, [R-(R*,S*)]-2,2-Dichloro-N-[1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl ]acetamide
2,2-Dichloro-N-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl)acetamide
2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamid
| Melting Point | 153 ° |
| Density | 1.451±0.06 g/cm3(Zvakafanotaurwa)1.1782(yakaomarara fungidziro) |
| kuchengetedza temp | 2-8°C |
| solubility | Soluble mu ethanol kusvika 25mM uye muDMSO kusvika ku100mM |
| optical chiitiko | N/A |
| Chitarisiko | Kuchena kusvika Kuchena-Kuchena |
| Kuchena | ≥98% |
Florfenicol is wide-spectrum fluorinated antibiotic uye inobva kune thiamphenicol (Item No. 21357).Inoshanda kurwisa makiriniki emunhu ega eteric bacteria, anosanganisira E. coli, Klebsiella, Enterobacter, Citrobacter, P. mirabilis, uye Salmonella (MIC50s = 6.3-12.5 μg/ml).Florfenicol inoshandawo pakurwisa zvirwere zvakasiyana-siyana zveBovine nenguruve, kusanganisira P. multocida, A. pleuropneumoniae, uye B. bronchiseptica (MIC).50s = 0.25-4 μg/ml).Inodzivisa peptidyl transferase basa mu70S ribosomes yakaparadzaniswa kubva kuE. coli kana ichishandiswa pamusangano we 1 mM.Mishonga ine florfenicol yakashandiswa mukurapa kwechirwere chekufema mumombe.
Imhando yemishonga inorwisa mabhakitiriya.Inoshandiswa semishonga inorwisa mabhakitiriya yemhuka yekurapa zvirwere zvebhakitiriya zvenguruve, huku uye hove.Iine simba rakanaka mukurapa chirwere chetachiona chenguruve, huku nehove chinokonzerwa nehutachiona hwehutachiona, kunyanya pakurapa zvirwere zvekufema uye zvirwere zvematumbo.
