Cas nhamba: 330784-47-9 Molecular Formula: C23H26ClN7O3
Melting Point | 150-152°C |
Density | 1.372 |
kuchengetedza temp | Yakavharwa pakaoma,Chengetedza mufiriji, pasi -20°C |
solubility | DMSO (Zvishoma), Methanol (Zvishoma, Kupisa) |
optical chiitiko | N/A |
Chitarisiko | Kuchena kusvika Kuchena-Kuchena |
Kuchena | ≥98% |
(Zepeed) yakagamuchirwa neKorea Health Ministry yekurapa erectile dysfunction (ED) muna Nyamavhuvhu 2011.is a yakasarudzika mhando 5 phosphodiesterase (PDE5) inhibitor.inonzi ndiyo inonyanya kusarudza PDE5 inhibitor pamusika.Kutanga kweTmax uye hafu yeupenyu zvakare inosiyana pakati peakashambadzirwa PDE5 inhibitors.Sildenafil ane Tmaxpa 1 h nehafu-hupenyu hwe3-5 h.Vardenafil yakangofanana neTmaxye0.6 h nehafu-hupenyu hwe4-6 h.Tadalafil ine hafu yakareba-yehupenyu pakati pemishonga inotengeswa ine hafu yeupenyu hwe17 h.ane kukurumidza kutanga kwechiito kusvika kuTmaxmu0.6 h nehafu yehupenyu hwe1.2 h.A synthesis ye (TA-1790) inotsanangurwa muzvinyorwa zvepatent.Nzira huru yekubvisa ndeye bile uye tsvina.yakawanikwa zvakare kuti yakatorwazve kuburikidza ne enterohepatic recirculation.
A phosphodiesterase (PDE5) inhibitor, inoshandiswa kurapa erectile dysfunction.
inonyatso kusarudza PDE5 inhibitor ine IC50 ye1 nM.