Cas nhamba: 330784-47-9 Molecular Formula: C23H26ClN7O3

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Cas nhamba: 330784-47-9 Molecular Formula: C23H26ClN7O3

Tsanangudzo Pfupi:

Cas nhamba: 330784-47-9

Kemikari Zita:

Molecular Formula:C23H26ClN7O3

Anoreva zvakafanana:(S) -2-(2-Hydroxymethyl-1-pyrrolidinyl) -4-(3-chloro-4-methoxybenzylamino) -5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidine

4--[(3-Chloro-4-methoxybenzyl) amino] -2--[2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide


Product Detail

Product Tags

Products Specification

Melting Point 150-152°C
Density 1.372
kuchengetedza temp Yakavharwa pakaoma,Chengetedza mufiriji, pasi -20°C
solubility DMSO (Zvishoma), Methanol (Zvishoma, Kupisa)
optical chiitiko N/A
Chitarisiko Kuchena kusvika Kuchena-Kuchena
Kuchena ≥98%

pharmacodynamics

(Zepeed) yakagamuchirwa neKorea Health Ministry yekurapa erectile dysfunction (ED) muna Nyamavhuvhu 2011.is a yakasarudzika mhando 5 phosphodiesterase (PDE5) inhibitor.inonzi ndiyo inonyanya kusarudza PDE5 inhibitor pamusika.Kutanga kweTmax uye hafu yeupenyu zvakare inosiyana pakati peakashambadzirwa PDE5 inhibitors.Sildenafil ane Tmaxpa 1 h nehafu-hupenyu hwe3-5 h.Vardenafil yakangofanana neTmaxye0.6 h nehafu-hupenyu hwe4-6 h.Tadalafil ine hafu yakareba-yehupenyu pakati pemishonga inotengeswa ine hafu yeupenyu hwe17 h.ane kukurumidza kutanga kwechiito kusvika kuTmaxmu0.6 h nehafu yehupenyu hwe1.2 h.A synthesis ye (TA-1790) inotsanangurwa muzvinyorwa zvepatent.Nzira huru yekubvisa ndeye bile uye tsvina.yakawanikwa zvakare kuti yakatorwazve kuburikidza ne enterohepatic recirculation.

use

A phosphodiesterase (PDE5) inhibitor, inoshandiswa kurapa erectile dysfunction.

kushandiswa uye dosage

inonyatso kusarudza PDE5 inhibitor ine IC50 ye1 nM.

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